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Literature summary for 2.7.11.1 extracted from

  • Amick, G.D.; Reddy, S.A.G.; Damuni, Z.
    Protein phosphatase 2A is a specific protamine-kinase-inactivating phosphatase (1992), Biochem. J., 287, 1019-1022.
No PubMed abstract available
Search for more literature for 2.7.11.1

Inhibitors

Inhibitors Comment Organism Structure
additional information protein phosphatase 2B, 2C, catalytic subunit of protein phosphatase 1, protein tyrosine phosphatases (PTPase 1B and T-cell PTPase), pyruvate dehydrogenase phosphatase Bos taurus
Protein phosphatase 1b weak Bos taurus
Protein phosphatase 2A ATP; diphosphate; Mn2+ enhances inactivation rate; okadaic acid, microcystin-LR; protein phosphatase inhibitor 2 does not protect; rate of inactivation is unaffected by EDTA, EGTA, Mg2+, Ca2+; specific protamine kinase inhibitors Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Bos taurus 5829
-
soluble
-
 Bos taurus
-
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protamine
-
 Bos taurus ADP + O-phosphoprotamine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Bos taurus