Literature summary for 2.7.11.1 extracted from

Sells, M.A.; Knaus, U.G.; Bagrodia, S.; Ambrose, D.M.; Bokoch, G.M.; Chernoff, J.
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells (1997), Curr. Biol., 7, 202-210.

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Cloned(Commentary)

Cloned (Comment)	Organism
microinjection of activated Pak1 protein into quiescent Swiss 3T3 cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + protein	Homo sapiens	the enzyme regulates the structure of the actin cytoskeleton in mammalian cells, and may serve as an effector for effector for Cdc42 and Rac1 in proll motility	ADP + phosphoprotein	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q13153	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + protein	the enzyme regulates the structure of the actin cytoskeleton in mammalian cells, and may serve as an effector for effector for Cdc42 and Rac1 in proll motility	Homo sapiens	ADP + phosphoprotein	-	?

Synonyms

Synonyms	Comment	Organism
Pak1	-	Homo sapiens
serine/threonine-protein kinase PAK 1	-	Homo sapiens

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Release 2023.1 (January 2023)