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Literature summary for 2.7.1.82 extracted from

  • He, R.; Guo, W.; Zhang, D.
    An ethanolamine kinase Eki1 affects radial growth and cell wall integrity in Trichoderma reesei (2015), FEMS Microbiol. Lett., 362, fnv133.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene Treki1, subcloningin Escherichia coli strain DH5alpha Trichoderma reesei

Protein Variants

Protein Variants Comment Organism
additional information targeted deletion of gene Treki1 by DNA insertion, Protoplast preparation and DNA-mediated transformation Trichoderma reesei

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + ethanolamine Trichoderma reesei
-
ADP + O-phosphoethanolamine
-
?
ATP + ethanolamine Trichoderma reesei QM9414
-
ADP + O-phosphoethanolamine
-
?

Organism

Organism UniProt Comment Textmining
Trichoderma reesei
-
i.e. Hypocrea jecorina, ATCC 26921, gene Treki1
-
Trichoderma reesei QM9414
-
i.e. Hypocrea jecorina, ATCC 26921, gene Treki1
-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
Trichoderma reesei
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ethanolamine
-
Trichoderma reesei ADP + O-phosphoethanolamine
-
?
ATP + ethanolamine
-
Trichoderma reesei QM9414 ADP + O-phosphoethanolamine
-
?

Synonyms

Synonyms Comment Organism
EKI1
-
Trichoderma reesei
Treki1
-
Trichoderma reesei

General Information

General Information Comment Organism
malfunction the gene Treki deletion mutant strain is less sensitive to cell wall stressors calcofluor white and Congo red and releases fewer protoplasts during cell wall digestion than the parent strain QM9414. The expression levels of five genes that encode chitin synthases are drastically increased in the Treki1 mutant, the chitin content is also increased in the null mutant of Treki1 comparing to the parent strain, and the Treki1 mutant exhibits defects in radial growth, conidiation and the accumulation of ethanolamine, phenotype overview Trichoderma reesei
metabolism catalyzes the committed step of phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway Trichoderma reesei
physiological function the enzyme plays a key role in growth and development and in the maintenance of cell wall integrity in Trichoderma reesei Trichoderma reesei