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Literature summary for 2.7.1.78 extracted from

  • Fanta, M.; Zhang, H.; Bernstein, N.; Glover, M.; Karimi-Busheri, F.; Weinfeld, M.
    Production, characterization, and epitope mapping of monoclonal antibodies against human polydeoxyribonucleotide kinase (2001), Hybridoma, 20, 237-242.
    View publication on PubMed
Search for more literature for 2.7.1.78

Cloned(Commentary)

Cloned (Comment) Organism
expression as soluble His-tagged protein in Escherichia coli Homo sapiens
expression of truncated enzyme, residue Met140 to C-terminus, in Escherichia coli Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 5'-dephospho-DNA Homo sapiens involved in repair of DNA single strand breaks ADP + 5'-phospho-DNA
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant His-tagged full length enzyme and recombinant truncated enzyme from Escherichia coli Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5'-dephospho-DNA
-
 Homo sapiens ADP + 5'-phospho-DNA
-
 ?
ATP + 5'-dephospho-DNA involved in repair of DNA single strand breaks Homo sapiens ADP + 5'-phospho-DNA
-
 ?
additional information enzyme also has DNA 3'-phosphatase activity Homo sapiens ?
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 ?

Subunits

Subunits Comment Organism
More epitope-mapping using specific monoclonal antibody Homo sapiens

Synonyms

Synonyms Comment Organism
More enzyme also possesses a 3'-phosphatase activity Homo sapiens