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Literature summary for 2.7.1.68 extracted from
- Type I phosphatidylinositol 4-phosphate 5-kinase gamma is required for neuronal migration in the mouse developing cerebral cortex (2013), Eur. J. Neurosci., 38, 2659-2671.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HeLa cells | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | Mus musculus | - |
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebral cortex | - |
Mus musculus | - |
| glial cell | - |
Mus musculus | - |
| neuroblast | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
Mus musculus | ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PIP5KIgamma | - |
Mus musculus |
| type I phosphatidylinositol 4-phosphate 5-kinase gamma | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme knockdown affects the recruitment of talin and focal adhesion kinase to the plasma membrane | Mus musculus |
| physiological function | the enzyme plays an essential role in neuronal migration, possibly through recruitment of adhesion components to the plasma membrane | Mus musculus |
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Release 2023.1 (January 2023)
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