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Literature summary for 2.7.1.68 extracted from

  • Sun, Y.; Hedman, A.C.; Tan, X.; Schill, N.J.; Anderson, R.A.
    Endosomal type Igamma PIP 5-kinase controls EGF receptor lysosomal sorting (2013), Dev. Cell, 25, 144-155.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.68

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome
-
 Homo sapiens 5768
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 x * 100000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate Homo sapiens
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PIPKIgammai5
-
 Homo sapiens
type I gamma phosphatidylinositol phosphate 5-kinase i5
-
 Homo sapiens
type Igamma PIP 5-kinase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme and sorting nexin 5 protein form a signaling nexus that controls epidermal growth factor receptor endosomal sorting, degradation, and signaling Homo sapiens