Literature summary for 2.7.1.68 extracted from

Deng, L.; Sugiura, R.; Ohta, K.; Tada, K.; Suzuki, M.; Hirata, M.; Nakamura, S.; Shuntoh, H.; Kuno, T.
Phosphatidylinositol-4-phosphate 5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway (2005), J. Biol. Chem., 280, 27561-27568.

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Protein Variants

Protein Variants	Comment	Organism
additional information	mutant its3-1 shows defective PIP5K activity and sensitivity to micafungin, aculeacin A, and BE49385A	Schizosaccharomyces pombe

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	not inhibited by micafungin	Schizosaccharomyces pombe
ZnSO4	sensitive to 9 mM ZnSO4	Schizosaccharomyces pombe

Organism

Organism	UniProt	Comment	Textmining
Schizosaccharomyces pombe	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	-	Schizosaccharomyces pombe	ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate	-	?

Synonyms

Synonyms	Comment	Organism
phosphatidylinositol-4-phosphate 5-kinase	-	Schizosaccharomyces pombe
PIP5K	-	Schizosaccharomyces pombe

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Schizosaccharomyces pombe

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Release 2023.1 (January 2023)