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Literature summary for 2.7.1.68 extracted from

  • Loijens, J.C.; Anderson, R.A.
    Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family (1996), J. Biol. Chem., 271, 32937-32943.
    View publication on PubMed
Search for more literature for 2.7.1.68

Cloned(Commentary)

Cloned (Comment) Organism
enzyme form PIP5KIalpha Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
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 Bos taurus 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate Bos taurus the product 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate is a key precursor in phosphoinositide signaling that also regulates some proteins and cellular processes directly ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
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 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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-
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Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain moderate expression of PIP5KIbeta, low expression of PIP5KIalpha Bos taurus
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erythrocyte
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 Bos taurus
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heart high expression of PIP5KIbeta and PIP5KIalpha Bos taurus
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kidney high expression of PIP5KIbeta Bos taurus
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liver low expression of PIP5KIalpha Bos taurus
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lung low expression of PIP5KIalpha Bos taurus
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pancreas moderate expression of PIP5KIbeta, high expression of PIP5KIalpha Bos taurus
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placenta high expression of PIP5KIbeta Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 Bos taurus ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate the product 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate is a key precursor in phosphoinositide signaling that also regulates some proteins and cellular processes directly Bos taurus ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?