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Literature summary for 2.7.1.67 extracted from

  • Sinha, R.K.; Bojjireddy, N.; Kulkarni, D.; Ratheesh, A.; Chiplunkar, S.V.; Gude, R.; Subrahmanyam, G.
    Type II phosphatidylinositol 4-kinase beta is an integral signaling component of early T cell activation mechanisms (2013), Biochimie, 95, 1560-1566.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol Homo sapiens
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
phosphatidylinositol 4-kinase beta
-
 Homo sapiens
PtdIns 4-kinase beta
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme is associated with actin cytoskeleton and cell adhesion, required for CD3 receptor induced calcium release, and a key component in early T cell activation signaling cascades Homo sapiens