Literature summary for 2.7.1.67 extracted from

Buckley, J.T.
Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP and related compounds (1977), Biochim. Biophys. Acta, 498, 1-9.

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Inhibitors

Inhibitors	Comment	Organism	Structure
5'-AMP	0.5 mM, 10% inhibition	Homo sapiens
adenosine	0.5 mM, 67% inhibition	Homo sapiens
ADP	0.5 mM, 58% inhibition	Homo sapiens
Caffeine	6.5 mM, 18% inhibition	Homo sapiens
cAMP	0.5 mM, 32% inhibition	Homo sapiens
GDP	0.5 mM, 4% inhibition	Homo sapiens
theophylline	2 mM, 21% inhibition	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol	-	Homo sapiens	ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	-	?

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Release 2023.1 (January 2023)