Protein Variants | Comment | Organism |
---|---|---|
D176V | the mutation leads to impaired N-acetylmannosamine kinase activity (40.58% of wild type activity) | Homo sapiens |
V572L | the mutation leads to impaired N-acetylmannosamine kinase activity (15.9% of wild type activity) | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Golgi membrane | - |
Homo sapiens | 139 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + N-acyl-D-mannosamine | Homo sapiens | - |
ADP + N-acyl-D-mannosamine 6-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y223 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + N-acyl-D-mannosamine | - |
Homo sapiens | ADP + N-acyl-D-mannosamine 6-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GNE | - |
Homo sapiens |
UDP-N-acetylglucosamine2-epimerase/N-acetylmannosamine kinase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme mutation affects beta1-integrin-mediated cell adhesion process | Homo sapiens |