Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.6 extracted from

  • Zenke, F.T.; Engels, R.; Vollenbroich, V.; Meyer, J.; Hollenberg, C.P.; Breunig, K.D.
    Activation of Gal4p by galactose-dependent interaction of galactokinase and Gal80p (1996), Science, 272, 1662-1665.
    View publication on PubMed
Search for more literature for 2.7.1.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + galactose Saccharomyces cerevisiae
-
 ADP + alpha-D-galactose 1-phosphate
-
 ?
additional information Saccharomyces cerevisiae galactokinase Gal1p is a regulator of transcription. Gal1p activates Gal4p, the activator of GAL genes. Gal1p activates Gal4p by direct interaction with the Gal4p inhibitor Gal80p. Interaction requires galactose, adenosine triphosphate and the regulatory function of Gal1p. The gal1p-gal80p complex formation results in the inactivation of Gal80p, thereby transmitting the galactose signal to Gal4p ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-galactose
-
 Saccharomyces cerevisiae ADP + alpha-D-galactose 1-phosphate
-
 ?
ATP + galactose
-
 Saccharomyces cerevisiae ADP + alpha-D-galactose 1-phosphate
-
 ?
additional information galactokinase Gal1p is a regulator of transcription. Gal1p activates Gal4p, the activator of GAL genes. Gal1p activates Gal4p by direct interaction with the Gal4p inhibitor Gal80p. Interaction requires galactose, adenosine triphosphate and the regulatory function of Gal1p. The gal1p-gal80p complex formation results in the inactivation of Gal80p, thereby transmitting the galactose signal to Gal4p Saccharomyces cerevisiae ?
-
 ?