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Literature summary for 2.7.1.48 extracted from

  • Vidair, C.; Rubin, H.
    Mg2+ as activator of uridine phosphorylation in coordination with other cellular responses to growth factors (2005), Proc. Natl. Acad. Sci. USA, 102, 662-666.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
ATP inhibitory when not complexed with Mg2+ Mus musculus
CTP feedback inhibition, most effective in the absence of Mg2+ Mus musculus
UTP feedback inhibition, most effective in the absence of Mg2+ Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ in complex with ATP Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + cytidine Mus musculus rate limiting enzyme of the pyrimidine-nucleotide salvage pathway ADP + CMP
-
?
ATP + uridine Mus musculus rate limiting enzyme of the pyrimidine-nucleotide salvage pathway ADP + UMP
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BALB/3T3 cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + cytidine
-
Mus musculus ADP + CMP
-
?
ATP + cytidine rate limiting enzyme of the pyrimidine-nucleotide salvage pathway Mus musculus ADP + CMP
-
?
ATP + uridine
-
Mus musculus ADP + UMP
-
?
ATP + uridine rate limiting enzyme of the pyrimidine-nucleotide salvage pathway Mus musculus ADP + UMP
-
?