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Literature summary for 2.7.1.48 extracted from
- Properties of uridine-cytidine kinase derived from L1210 leukemia cells (1980), Cancer Res., 40, 3559-3563.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5'-Azido-5'-deoxycytidine | - |
Mus musculus |  |
| 5'-Azido-5'-deoxyuridine | - |
Mus musculus | |
| 5'-O-Nitro-5-fluorouridine | - |
Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.15 | - |
cytidine | - |
Mus musculus | |
| 0.23 | - |
uridine | - |
Mus musculus | |
| 0.349 | - |
ATP | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
several isoenzymes | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leukemia cell line | L-1210 cell line | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + cytidine | - |
Mus musculus | ADP + CMP | - |
? | |
| ATP + uridine | - |
Mus musculus | ADP + UMP | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.037 | - |
5'-Azido-5'-deoxycytidine | - |
Mus musculus | |
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