Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CTP | 80-85% inhibition at approx. 2 mM | Geobacillus stearothermophilus | |
CTP | complete inhibition at approx. 2 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.21 | - |
uridine | - |
Geobacillus stearothermophilus | |
0.27 | - |
uridine | 37°C | Rattus norvegicus | |
0.64 | - |
uridine | - |
Geobacillus stearothermophilus | |
1.6 | - |
uridine | - |
Geobacillus stearothermophilus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
109000 | - |
sucrose density gradient centrifugation | Geobacillus stearothermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
streptomycin, ammonium sulfate, calcium phosphate, DEAE-cellulose | Geobacillus stearothermophilus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + uridine | - |
Rattus norvegicus | ADP + UMP | - |
? | |
ATP + uridine | - |
Geobacillus stearothermophilus | ADP + UMP | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
higher activity than at 10°C and 37°C | Geobacillus stearothermophilus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
59.5 | - |
no loss of activity after 30 min | Geobacillus stearothermophilus |
59.5 | - |
79% loss of activity after 4 min | Rattus norvegicus |