Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | forward reaction is not activated by ATP, cysteine, histidine, adenylic acid or phosphate | Oryctolagus cuniculus |
General Stability | Organism |
---|---|
stable to 3-4 h dialysis against distilled water, prolonged or repeated dialysis inactivates | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | inhibits forward reaction above 2 mM | Oryctolagus cuniculus | |
Cu2+ | weak, 0.1 mM | Oryctolagus cuniculus | |
Mg2+ | inhibits reverse reaction at 0.5 mM, forward reaction: activation | Oryctolagus cuniculus | |
Mn2+ | inhibits forward reaction above 0.5 mM | Oryctolagus cuniculus | |
additional information | not inhibited by 8 mM fluoride, cysteine, histidine, adenylic acid or phosphate | Oryctolagus cuniculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | activation of forward reaction, optimal concentration: 1 mM, inhibition of reverse reaction, Mg2+ forms a complex with the product glucose-1,6-bisphosphate | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial, not separated from phosphoglucomutase | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | muscles of back and hind legs | Oryctolagus cuniculus | - |
Storage Stability | Organism |
---|---|
6°C, within 1 week, inactivation | Oryctolagus cuniculus |
frozen, partially purified preparation, at least 4 weeks, stable | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 1-phosphate + D-glucose 1-phosphate | - |
Escherichia coli | D-glucose + D-glucose 1,6-bisphosphate | - |
? | |
D-glucose 1-phosphate + D-glucose 1-phosphate | - |
Oryctolagus cuniculus | D-glucose + D-glucose 1,6-bisphosphate | - |
r |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Oryctolagus cuniculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
forward reaction, in the presence of Mg2+ | Oryctolagus cuniculus |