Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.40 extracted from

  • Kumar, N.S.; Amandoron, E.A.; Cherkasov, A.; Finlay, B.B.; Gong, H.; Jackson, L.; Kaur, S.; Lian, T.; Moreau, A.; Labriere, C.; Reiner, N.E.; See, R.H.; Strynadka, N.C.; Thorson, L.; Wong, E.W.; Worrall, L.; Zoraghi, R.; Young, R.N.
    Optimization and structure-activity relationships of a series of potent inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as novel antimicrobial agents (2012), Bioorg. Med. Chem., 20, 7069-7082.
    View publication on PubMed
Search for more literature for 2.7.1.40

Application

Application Comment Organism
drug development the enzyme is a potential target for development of novel antibiotics Staphylococcus aureus

Inhibitors

Inhibitors Comment Organism Structure
(5-bromo-2-hydroxyphenyl)([(E)-[1-(1-methyl-1H-indol-2-yl)ethylidene]amino]oxy)methanone 34% inhibition at 0.01 mM Staphylococcus aureus
(5-bromo-2-methoxyphenyl)([(E)-[1-(1-methyl-1H-indol-2-yl)ethylidene]amino]oxy)methanone 33% inhibition at 0.01 mM Staphylococcus aureus
(E)-5-bromo-2-hydroxy-N'-(1-(4,5,6-trifluoro-1Hindol-2-yl)ethylidene)benzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-2-hydroxy-N'-(1-(5-hydroxy-1H-indol-2-yl)ethylidene)benzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-2-hydroxy-N'-(1-(5-methoxy-1H-indol-2-yl)ethylidene)benzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(5,6-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(5-bromo-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(5-bromo-1H-indol-2-yl)propylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(5-chloro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(5-fluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(6-bromo-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-5-bromo-N'-(1-(7-fluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide 39% inhibition at 500 nM Staphylococcus aureus
(E)-N'-((1H-indol-2-yl)methylene)-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-2-hydroxy-5-chlorobenzohydrazide 36% inhibition at 0.001 mM Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-2-hydroxy-5-iodobenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-3,5-dibromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-3,5-dibromo-2-methoxybenzohydrazide 57% inhibition at 0.001 mM Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-3-bromobenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-4-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-(prop-2-ynyloxy)benzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-hydroxy-4-methoxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-methoxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)benzohydrazide 28% inhibition at 0.01 mM Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)ethylidene)picolinohydrazid 15% inhibition at 0.01 M Staphylococcus aureus
(E)-N'-(1-(1H-indol-2-yl)propylidene)-5-bromo-2-hydroxybenzohydrazide crystal structure determination of the inhibitor compound Staphylococcus aureus
(E)-N'-[(1H-indol-2-yl)methylene]-5-bromo-2-methoxybenzohydrazide
-
 Staphylococcus aureus
(E)-N'-[1-(1H-indol-2-yl)ethylidene]-2-hydroxy-3,5-diisopropylbenzohydrazide 40% inhibition at 0.01 mM Staphylococcus aureus
(E)-N'-[1-(1H-indol-2-yl)ethylidene]-5-bromo-2-ethoxybenzohydrazide
-
 Staphylococcus aureus
(E/Z)-N'-((1H-indol-2-yl)(phenyl)methylene)-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
(Z)-N'-(1-(1H-indol-2-yl)-2,2-dimethylpropylidene)-5-bromo-2-hydroxybenzohydrazide crystal structure determination of the inhibitor compound Staphylococcus aureus
2-hydroxy-5-iodo-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
2-[(1E)-1-[2-[(5-bromo-2-methoxyphenyl)(dioxido-l6-sulfanylidene)methyl]hydrazinylidene]ethyl]-1H-indole 12% inhibition at 0.01 mM Staphylococcus aureus
2-[(1E)-1-[2-[(5-bromo-2-methoxyphenyl)(dioxido-l6-sulfanylidene)methyl]hydrazinylidene]ethyl]-4,5-difluoro-1H-indole 11% inhibition at 0.01 mM Staphylococcus aureus
3-hydroxy-N'-[(1E)-1-(1H-indol-2-yl)ethylidene]naphthalene-2-carbohydrazide
-
 Staphylococcus aureus
3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)ethylidene]naphthalene-2-carbohydrazide
-
 Staphylococcus aureus
3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)propylidene]naphthalene-2-carbohydrazide
-
 Staphylococcus aureus
3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1H-indol-2-yl)propylidene]naphthalene-2-carbohydrazide
-
 Staphylococcus aureus
4-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide 611% inhibition at 500 nM Staphylococcus aureus
4-hydroxy-N'-[(1E)-1-(1H-indol-2-yl)ethylidene]-1,10-biphenyl-3-carbohydrazide 20% inhibition at 0.01 mM Staphylococcus aureus
5-bromo-2-(ethoxymethoxy)-N'-((1E)-1-(1H-indol-2-yl)ethylidene)benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-4-methoxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-benzimidazol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)propylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(5-hydroxy-1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(5-iodo-1H-indol-2-yl)ethylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-(5-methoxy-1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide 54% inhibition at 0.001 mM Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(1E)-1-[5-(trifluoromethyl)-1Hindol-2-yl]ethylidene]benzohydrazide 46% inhibition at 0.01 mM Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(E)-(1-methyl-1H-indol-2-yl)(phenyl)methylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-2-hydroxy-N'-[(E)-(1-methyl-1H-indol-2-yl)methylidene]benzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(1H-indol-2-yl)ethylidene]-2-methoxy-N-methylbenzohydrazide 33% inhibition at 0.001 mM Staphylococcus aureus
5-bromo-N'-[(1E)-1-(4,5-difluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(5,6-difluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)propylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(5-chloro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(5-fluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
5-bromo-N'-[(1E)-1-(6-bromo-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
additional information inhibitor development, synthesis, optimization, and structure-activity relationship analysis, inhibitor potencies in growth inhibition of strains RN4220, ATCC 25923, and ATCC 29213, overview. No inhibition by (E)-5-bromo-2-hydroxy-N'-(1-(5-phenyl-1H-indol-2-yl)ethylidene)benzohydrazide, (Z)-N'-(1-(1H-indol-2-yl)-2,2-dimethylpropylidene)-5-bromo-2-hydroxybenzohydrazide, and 5-bromo-N'-[(1E)-2,2-dimethyl-1-(1-methyl-1H-indol-2-yl)propylidene]-2-hydroxybenzohydrazide Staphylococcus aureus
N'-[(1E)-1-(1,3-benzothiazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(1,3-benzoxazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide 26% inhibition at 500 nM Staphylococcus aureus
N'-[(1E)-1-(1-benzothiophen-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)ethylidene]-3-hydroxynaphthalene-2-carbohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)propylidene]-3-hydroxynaphthalene-2-carbohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(5-bromo-1H-indol-2-yl)ethylidene]-3-hydroxynaphthalene-2-carbohydrazide
-
 Staphylococcus aureus
N'-[(1E)-1-(5-bromo-1H-indol-2-yl)propylidene]-3-hydroxynaphthalene-2-carbohydrazide
-
 Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
 MRSA
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000015
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-2-hydroxy-N'-(1-(4,5,6-trifluoro-1Hindol-2-yl)ethylidene)benzohydrazide
0.000017
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(6-bromo-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000018
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(5-bromo-1H-indol-2-yl)propylidene]-3-hydroxynaphthalene-2-carbohydrazide
0.00002
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(5,6-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000024
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(6-bromo-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000024
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000026
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(5-bromo-1H-indol-2-yl)ethylidene]-3-hydroxynaphthalene-2-carbohydrazide
0.000031
-
 pH 7.5, 30°C Staphylococcus aureus 3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1H-indol-2-yl)propylidene]naphthalene-2-carbohydrazide
0.000042
-
 pH 7.5, 30°C Staphylococcus aureus 3-hydroxy-N'-[(1E)-1-(1H-indol-2-yl)ethylidene]naphthalene-2-carbohydrazide
0.000043
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(5-iodo-1H-indol-2-yl)ethylidene]benzohydrazide
0.000049
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(5-fluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000049
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(5-bromo-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000049
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-[(1H-indol-2-yl)methylene]-5-bromo-2-methoxybenzohydrazide
0.000052
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(5-chloro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
0.000052
-
 pH 7.5, 30°C Staphylococcus aureus 3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)propylidene]naphthalene-2-carbohydrazide
0.000055
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
0.000059
-
 pH 7.5, 30°C Staphylococcus aureus 3-hydroxy-N'-[(1E)-1-(4,5,6-trifluoro-1-methyl-1H-indol-2-yl)ethylidene]naphthalene-2-carbohydrazide
0.000061
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(5,6-difluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000063
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-[1-(1H-indol-2-yl)ethylidene]-5-bromo-2-ethoxybenzohydrazide
0.000064
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-(prop-2-ynyloxy)benzohydrazide
0.000074
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-3,5-dibromo-2-hydroxybenzohydrazide
0.000079
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)propylidene]-3-hydroxynaphthalene-2-carbohydrazide
0.000085
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-hydroxybenzohydrazide
0.000091
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
0.000115
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)ethylidene]-3-hydroxynaphthalene-2-carbohydrazide
0.000126
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)propylidene)-5-bromo-2-hydroxybenzohydrazide
0.000145
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(4,5-difluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000146
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000151
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-2-hydroxy-5-iodobenzohydrazide
0.000165
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(5-fluoro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000168
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(5-bromo-1-methyl-1H-indol-2-yl)propylidene]-2-hydroxybenzohydrazide
0.000178
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-2-hydroxy-N'-(1-(5-methoxy-1H-indol-2-yl)ethylidene)benzohydrazide
0.000182
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-methoxybenzohydrazide
0.000214
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-2-hydroxy-N'-(1-(5-hydroxy-1H-indol-2-yl)ethylidene)benzohydrazide
0.000224
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(1,3-benzothiazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
0.000227
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-benzimidazol-2-yl)ethylidene]benzohydrazide
0.000228
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-N'-[(1E)-1-(5-chloro-1-methyl-1H-indol-2-yl)ethylidene]-2-hydroxybenzohydrazide
0.000251
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-(ethoxymethoxy)-N'-((1E)-1-(1H-indol-2-yl)ethylidene)benzohydrazide
0.000286
-
 pH 7.5, 30°C Staphylococcus aureus N'-[(1E)-1-(1-benzothiophen-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide
0.000324
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-5-bromo-2-hydroxy-4-methoxybenzohydrazide
0.000381
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
0.000445
-
 pH 7.5, 30°C Staphylococcus aureus (E/Z)-N'-((1H-indol-2-yl)(phenyl)methylene)-5-bromo-2-hydroxybenzohydrazide
0.000451
-
 pH 7.5, 30°C Staphylococcus aureus (E)-5-bromo-N'-(1-(5-bromo-1H-indol-2-yl)propylidene)-2-hydroxybenzohydrazide
0.000461
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)propylidene]benzohydrazide
0.000483
-
 pH 7.5, 30°C Staphylococcus aureus 2-hydroxy-5-iodo-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
0.000794
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(1E)-1-(5-methoxy-1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
0.000841
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-4-methoxy-N'-[(1E)-1-(1-methyl-1H-indol-2-yl)ethylidene]benzohydrazide
0.000863
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-((1H-indol-2-yl)methylene)-5-bromo-2-hydroxybenzohydrazide
0.001312
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-4-bromo-2-hydroxybenzohydrazide
0.003087
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(E)-(1-methyl-1H-indol-2-yl)methylidene]benzohydrazide
0.006043
-
 pH 7.5, 30°C Staphylococcus aureus 5-bromo-2-hydroxy-N'-[(E)-(1-methyl-1H-indol-2-yl)(phenyl)methylidene]benzohydrazide
0.00815
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-3-bromobenzohydrazide
0.008615
-
 pH 7.5, 30°C Staphylococcus aureus (E)-N'-(1-(1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide