Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate | Homo sapiens | - |
ATP + pyruvate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
squamous cell carcinoma cell | squamous cell carcinoma of tongue | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate | - |
Homo sapiens | ATP + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKM2 | - |
Homo sapiens |
pyruvate kinase type M2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | in tongue squamous cell carcinoma cell lines, PKM2 expression is reduced in response to miR-133a and miR-133b precursors transfection | down |
Homo sapiens | PKM2 is overexpressed in tongue squamous cell carcinoma cells and is associated with the downregulation of miR-133a and miR-133b | up |