Any feedback?
Literature summary for 2.7.1.40 extracted from
- The quaternary structure of pyruvate kinase type 1 from Escherichia coli at low nanomolar concentrations (2010), Biochimie, 92, 116-120.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| D-fructose 1,6-bisphosphate | heterotropic activator of PK1, the modulation of oligomeric state by the allosteric effector D-fructose 1,6-bisphosphate does not occur at a concentration of 10 nM or above | Escherichia coli |  |
| phosphoenolpyruvate | homotropic activator of PK1, the modulation of oligomeric state by the allosteric effector phosphoenolpyruvate does not occur at a concentration of 10 nM or above | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 195000 | - |
- |
Escherichia coli |
| 203000 | - |
calculated from amino acid sequence | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | - |
Escherichia coli | ATP + pyruvate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetramer | - |
Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PK1 | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Escherichia coli | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
