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Literature summary for 2.7.1.40 extracted from
- Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism (2008), Anticancer Res., 27, 3963-3971.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| A-Raf | - |
Mus musculus | |
| D-fructose 1,6-bisphosphate | - |
Mus musculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-Ala | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Mus musculus | - |
| NIH-3T3 cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | - |
Mus musculus | ATP + pyruvate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetramer | - |
Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| M2-PK | - |
Mus musculus |
| pyruvate kinase type M2 | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Mus musculus | |
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