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Literature summary for 2.7.1.40 extracted from

  • Vetter, R.A.H.; Buchholz, F.
    Catalytic properties of two pyruvate kinase isoforms in Nordic krill, Meganyctiphanes norvegica, with respect to seasonal temperature adaptation (1997), Comp. Biochem. Physiol. A, 116A, 1-10.
No PubMed abstract available
Search for more literature for 2.7.1.40

Activating Compound

Activating Compound Comment Organism Structure
D-fructose 1,6-diphosphate only PK II, shifting sigmoidal kinetics to hyperbolic curves, decrease in Km Meganyctiphanes norvegica

Inhibitors

Inhibitors Comment Organism Structure
oxalate PK I, 80% inhibition at 0.3 mM, PK II, 50% inhibition at 0.3 mM Meganyctiphanes norvegica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.024
-
 phosphoenolpyruvate 15°, pH 7.0, isoform PK I, in winter Meganyctiphanes norvegica
0.033
-
 phosphoenolpyruvate 15°, pH 7.0, isoform PK I, in summer Meganyctiphanes norvegica
0.181
-
 phosphoenolpyruvate 15°, pH 7.0, isoform PK II, in summer Meganyctiphanes norvegica
0.193
-
 phosphoenolpyruvate 15°, pH 7.0, isoform PK II, in winter Meganyctiphanes norvegica

Organism

Organism UniProt Comment Textmining
Meganyctiphanes norvegica
-
 nordic krill, isoforms PK I and PK II
-

Source Tissue

Source Tissue Comment Organism Textmining
cephalothorax isoform PK II Meganyctiphanes norvegica
-
muscle abdominal muscle, PK I Meganyctiphanes norvegica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphoenolpyruvate
-
 Meganyctiphanes norvegica ATP + pyruvate
-
 ?