Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NAD+ | 0.5 mM, activation to 125%, activity with pyridoxine | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-hydroxytryptamine | 0.5 mM, 11% inhibition of activity with pyridoxine, 81% inhibition of activity with pyridoxal | Rattus norvegicus | |
NADH | 0.5 mM, 14% inhibition of activity with pyridoxine, 11% inhibition of activity with pyridoxal | Rattus norvegicus | |
picolinate | 0.5 mM, 95% inhibition of activity with pyridoxine, 97% inhibition of activity with pyridoxal | Rattus norvegicus | |
pyridoxine | substrate inhibition above 0.2 mM | Rattus norvegicus | |
quinolinate | 0.5 mM, 82% inhibition of activity with pyridoxine, 82% inhibition of activity with pyridoxal | Rattus norvegicus | |
tryptamine | no inhibition of activity with pyridoxine, 72% inhibition of activity with pyridoxal | Rattus norvegicus | |
xanthurenate | 0.5 mM, 19% inhibition of activity with pyridoxine, 18% inhibition of activity with pyridoxal | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
pyridoxine | 37°C | Rattus norvegicus | |
0.19 | - |
pyridoxal | 37°C | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.27 | - |
reaction with pyridoxal | Rattus norvegicus |
1.42 | - |
reaction with pyridoxine | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyridoxal | - |
Rattus norvegicus | ADP + pyridoxal 5'-phosphate | - |
? | |
ATP + pyridoxine | - |
Rattus norvegicus | ADP + pyridoxine 5'-phosphate | - |
? |