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Literature summary for 2.7.1.33 extracted from

  • Leonardi, R.; Zhang, Y.M.; Lykidis, A.; Rock, C.O.; Jackowski, S.
    Localization and regulation of mouse pantothenate kinase 2 (2007), FEBS Lett., 581, 4639-4644.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
palmitoylcarnitine activates Mus musculus
palmitoylcarnitine activates Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
acetyl-CoA
-
Homo sapiens
acetyl-CoA
-
Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Mus musculus 5829
-
cytosol
-
Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain expression of PanK2 is higher in human brain compared to mouse brain Mus musculus
-
brain expression of PanK2 is higher in human brain compared to mouse brain Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pantothenate
-
Homo sapiens ADP + (R)-4'-phosphopantothenate
-
?
ATP + pantothenate
-
Mus musculus ADP + (R)-4-phosphopantothenate
-
?

Synonyms

Synonyms Comment Organism
hPANK2
-
Homo sapiens
mPanK2
-
Mus musculus
pantothenate kinase 2
-
Mus musculus
pantothenate kinase 2
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000625
-
-
Mus musculus acetyl-CoA
0.000125
-
-
Homo sapiens acetyl-CoA