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Literature summary for 2.7.1.33 extracted from

  • Chen, X.; Shen, D.; Zhou, B.
    Analysis of the temperature-sensitive mutation of Escherichia coli pantothenate kinase reveals YbjN as a possible protein stabilizer (2006), Biochem. Biophys. Res. Commun., 345, 834-842.
    View publication on PubMed
Search for more literature for 2.7.1.33

Protein Variants

Protein Variants Comment Organism
L236F temperature-sensitive mutant, inactive above 39°C Escherichia coli
R315C temperature-sensitive mutant, inactive above 39°C Escherichia coli
S176L temperature-sensitive mutant, inactive above 39°C Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 SDS-PAGE Escherichia coli
36300
-
 calculated from sequence of cDNA Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 K12 strain ts9
-

Purification (Commentary)

Purification (Comment) Organism
Ni-column chromatography Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-pantothenate
-
 Escherichia coli ADP + (R)-4'-phosphopantothenate
-
 ?

Synonyms

Synonyms Comment Organism
CoaA
-
 Escherichia coli
PanK
-
 Escherichia coli

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
30 42
-
 Escherichia coli

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
47
-
 loses kinase activity at temperatures higher than 47°C Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Escherichia coli