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Literature summary for 2.7.1.33 extracted from
- Pantothenate kinase regulation of the intracellular concentration of coenzyme A (2000), J. Biol. Chem., 275, 1377-1383.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| CoA | stimulates | Mus musculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetyl-CoA | strong | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q8K4K6 | isoforms mPanK1alpha, mPanK1beta | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | mainly isoform mPanK1alpha | Mus musculus | - |
| kidney | both isoforms | Mus musculus | - |
| liver | mainly isoform mPanK1beta | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-pantothenate | - |
Mus musculus | ADP + D-4'-phosphopantothenate | - |
? | |
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Release 2023.1 (January 2023)
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