Literature summary for 2.7.1.30 extracted from

Krakow, J.L.; Wang, C.C.
Purification and characterization of glycerol kinase from Trypanosoma brucei (1990), Mol. Biochem. Parasitol., 43, 17-25.

Search for more literature for 2.7.1.30

Inhibitors

Inhibitors	Comment	Organism	Structure
ADP	weak, competitive to ATP, uncompetitive to glycerol	Trypanosoma brucei
glycerol 3-phosphate	up to 10 mM, no product inhibition of the forward reaction	Trypanosoma brucei

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.17	-	glycerol	pH 9.0	Trypanosoma brucei
0.19	-	ATP	pH 7.4	Trypanosoma brucei
0.26	-	glycerol	pH 7.4, ATP, pH 9.0	Trypanosoma brucei

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
glycosome	-	Trypanosoma brucei	20015	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
53000	-	-	Trypanosoma brucei

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma brucei	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Trypanosoma brucei

Reaction

Reaction	Comment	Organism	Reaction ID
ATP + glycerol = ADP + sn-glycerol 3-phosphate	random bi bi mechanism	Trypanosoma brucei	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + glycerol	-	Trypanosoma brucei	ADP + sn-glycerol 3-phosphate	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 53000	Trypanosoma brucei

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7	9.5	-	Trypanosoma brucei

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Release 2023.1 (January 2023)