Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | F7EXV6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
INS-1 832/13 cell | - |
Rattus norvegicus | - |
pancreatic beta cell | - |
Mus musculus | - |
pancreatic beta cell | - |
Rattus norvegicus | - |
pancreatic islet | - |
Mus musculus | - |
pancreatic islet | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NAD+ | - |
Mus musculus | ADP + NADP+ | - |
? | |
ATP + NAD+ | - |
Rattus norvegicus | ADP + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATP: NAD(H) 2'-phosphotransferase | - |
Mus musculus |
ATP: NAD(H) 2'-phosphotransferase | - |
Rattus norvegicus |
NAD kinase | - |
Mus musculus |
NAD kinase | - |
Rattus norvegicus |
NADK | - |
Mus musculus |
NADK | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme regulates the size of the NADPH pool and insulin secretion in pancreatic beta-cells. Enzyme overexpression also protects beta-cells against oxidative damage by the redox cycling agent menadione and reverses menadione-mediated inhibition of glucose-stimulated insulin secretion | Mus musculus |
physiological function | the enzyme regulates the size of the NADPH pool and insulin secretion in pancreatic beta-cells. Enzyme overexpression also protects beta-cells against oxidative damage by the redox cycling agent menadione and reverses menadione-mediated inhibition of glucose-stimulated insulin secretion | Rattus norvegicus |