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Literature summary for 2.7.1.22 extracted from
- Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+ biosynthetic machinery in mammalian cells (2014), FEBS J., 281, 5104-5119.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | simple, fast and sensitive coupled fluorometric assay that enables simultaneous determination of nicotinamide phosphoribosyltransferase EC 2.4.2.12, quinolinate phosphoribosyltransferase EC 2.4.2.19, nicotinate phosphoribosyltransferase EC 6.3.4.21 and nicotinamide riboside kinase in whole-cell extracts and biological fluids yielding an overall picture of the tissue/cell-specific distribution of the activities of the various enzymes | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
| kidney | and liver, highest eypression | Homo sapiens | - |
| liver | and kidney, highest eypression | Homo sapiens | - |
| additional information | presence of quinolinate phosphoribosyltransferase and nicotinamide riboside kinase in all examined tissues/cell lines | Homo sapiens | - |
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Release 2023.1 (January 2023)
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