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Literature summary for 2.7.1.21 extracted from
- Serum thymidine kinase activity: analytical performance, age-related reference ranges and validation in chronic lymphocytic leukemia (2014), PLoS ONE, 9, e91647.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | serum TK1 activity displays a statistically significant decline from young (18-35 years) to middle-aged (36-60 years) and further on to elderly (60-86 years) healthy individuals. Age-related reference range is: <30 U/l for young, <25 U/l for middle-aged and <19 U/l for elderly. There is no difference in TK1 activity between the studied healthy men and women. In chronic lymphocytic leukemia patients, TK1 activity is the highest in the advanced Rai stages. TK1 is significantly elevated in CD38+/Zap70+ chronic lymphocytic leukemia patients, and shows significant correlation with white blood cell and absolute B-cell count | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
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