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Literature summary for 2.7.1.21 extracted from

  • Jagarlamudi, K.K.; Westberg, S.; Roennberg, H.; Eriksson, S.
    Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker (2014), BMC Vet. Res., 10, 228.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine serum TK1 protein and activity levels are significantly higher in canine mammary tumor than in healthy dogs. Major differences are found in the molecular forms of TK1 in acute lymphocytic leukemia, healthy, and in canine mammary tumor dogs, with a large fraction of inactive TK1 protein in in canine mammary tumor dogs. The serum TK1 protein assay can differentiate benign tumors (early stage tumors) from healthy more efficiently than the serum TK1 activity assay Canis lupus familiaris

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris E2QXP4
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Source Tissue

Source Tissue Comment Organism Textmining