Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thymidine | Equid alphaherpesvirus 4 | - |
ADP + thymidine 5'-phosphate | - |
? | |
ATP + thymidine | Equid alphaherpesvirus 4 TH20p | - |
ADP + thymidine 5'-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Equid alphaherpesvirus 4 | - |
- |
- |
Equid alphaherpesvirus 4 TH20p | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thymidine | - |
Equid alphaherpesvirus 4 | ADP + thymidine 5'-phosphate | - |
? | |
ATP + thymidine | - |
Equid alphaherpesvirus 4 TH20p | ADP + thymidine 5'-phosphate | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Equid alphaherpesvirus 4 |
General Information | Comment | Organism |
---|---|---|
malfunction | the thymidine kinase-deletion mutant WA79DELTATK shows more than 20fold increase in sensitivity towards acyclovir and is insensitive to ganciclovir | Equid alphaherpesvirus 4 |
physiological function | the virus-encoded thymidine kinase is an important determinant of the virus susceptibility to nucleoside analogues | Equid alphaherpesvirus 4 |