Application | Comment | Organism |
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medicine | Hsv1-tk mutants are present in multiple ganglia of an immunocompromised patient with a history of chronic Acv(r) skin lesions. Mutations in the thymidine kinase gene of herpes simplex virus type 1 explain in most cases of the virus resistance to acyclvir treatment. Mutants arise independently under drug selection and establish latency in human sensory ganglia alone or together with the wild-type virus | Human alphaherpesvirus 1 |
Organism | UniProt | Comment | Textmining |
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Human alphaherpesvirus 1 | P03176 | - |
- |
Source Tissue | Comment | Organism | Textmining |
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