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Literature summary for 2.7.1.20 extracted from

  • Matulenko, M.A.; Paight, E.S.; Frey, R.R.; Gomtsyan, A.; DiDomenico, S.; Jiang, M.; Lee, C.H.; Stewart, A.O.; Yu, H.; Kohlhaas, K.L.; Alexander, K.M.; McGaraughty, S.; Mikusa, J.; Marsh, K.C.; Muchmore, S.W.; Jakob, C.L.; Kowaluk, E.A.; Jarvis, M.F.; Bhagwat, S.S.
    4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors (2007), Bioorg. Med. Chem., 15, 1586-1605.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5'-amino-5'-deoxy-adenosine following systemic administration, adenosine kinase inhibitors can alleviate acute thermal nociception as measured by the hot-plate test in mice Mus musculus
5'-deoxy-5-iodotubercidin following systemic administration, adenosine kinase inhibitors can alleviate acute thermal nociception as measured by the hot-plate test in mice Mus musculus
5-iodotubercidin following systemic administration, adenosine kinase inhibitors can alleviate acute thermal nociception as measured by the hot-plate test in mice Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Mus musculus 5829
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-