Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5'-p-[(fluorosulfonyl)benzoyl]adenosine | incubation of 0.7 mg/ml Fn3KRP with 0.5 mM inhibitor results in significant activity loss compared with controls. The inhibitor inactivates Fn3KRP by modification of residues at the nucleotide-binding site | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.42 | - |
[lysozyme]-N6-D-psicosyl-L-lysine | pH 7.8, 30°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9HA64 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung cancer cell line | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [lysozyme]-N6-D-psicosyl-L-lysine | in contrast with free psicose-lysine, not all psicosamine residues in the glycated lysozyme substrate would be expected to be accessible to the Fn3KRP active site. In addition, local charge effects may influence the relative affinity for psicosamine residues at different sites in the lysozyme substrate | Homo sapiens | ADP + [lysozyme]-N6-(O3-phosphono-D-psicosyl)-L-lysine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FN3K-related protein | - |
Homo sapiens |
Fn3KRP | - |
Homo sapiens |
fructosamine 3-kinase-related protein | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Homo sapiens |