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Literature summary for 2.7.1.172 extracted from
- Fructosamine 3-kinase-related protein and deglycation in human erythrocytes (2004), Biochem. J., 382, 137-143.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-deoxy-1-morpholinopsicose | competitive inhibitor | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | FN3K-RP can act inside erythrocytes as a deglycating enzyme by converting ketoamines into unstable phosphate esters. Potential physiological substrates are psicosamines, which appear to be formed slowly from fructosamines | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9HA64 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | activity of fructosamine 3-kinase-related protein is several-fold higher than fructosamine 3-kinase | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | FN3K-RP can act inside erythrocytes as a deglycating enzyme by converting ketoamines into unstable phosphate esters. Potential physiological substrates are psicosamines, which appear to be formed slowly from fructosamines | Homo sapiens | ? | - |
? | |
| additional information | FN3K-RP progressively phosphorylates haemoglobin from erythrocytes that had been incubated with allose or ribose | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FN3K-RP | - |
Homo sapiens |
| fructosamine 3-kinase-related protein | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | FN3K-RP can act inside erythrocytes as a deglycating enzyme by converting ketoamines into unstable phosphate esters. Potential physiological substrates are psicosamines, which appear to be formed slowly from fructosamines | Homo sapiens |
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Release 2023.1 (January 2023)
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