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Literature summary for 2.7.1.163 extracted from

  • Dev, K.; Maheshwari, R.
    Silencing of hygromycin phosphotransferase (hph) gene during sexual cycle and its reversible inactivation in heterokaryon of Neurospora crassa (2003), Curr. Microbiol., 47, 220-225.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene hph, subcloning in strain DH5alpha, expression in Neurospora crassa 74-OR23-IVA and al-1,mcm Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information construction of a hygromycin-sensitive Neurospora crassa mutant heterokaryon strain by crossing of a wild-type strain and a stable hygromycin transformant, the enzyme can be reversibly inactivated, overview Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + hygromycin B Escherichia coli
-
ADP + 7''-O-phosphohygromycin B
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
gene hph
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + hygromycin B
-
Escherichia coli ADP + 7''-O-phosphohygromycin B
-
?

Synonyms

Synonyms Comment Organism
hygromycin phosphotransferase
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli