Literature summary for 2.7.1.154 extracted from

Wheeler, M.; Domin, J.
Recruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2 (2001), Mol. Cell. Biol., 21, 6660-6667.

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	interaction with Grb2 dramatically increases catalytic activity. Proline-rich motifs within the N-terminus of PI3K-C2beta mediate the association of this enzyme with activated EGF receptor and this interaction involves the Grb2 adaptor	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	PI3K-C2beta	-

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Release 2023.1 (January 2023)