Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.154 extracted from

  • Gaidarov, I.; Smith, M.E.K.; Domin, J.; Keen, J.H.
    The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking (2001), Mol. Cell, 7, 443-449.
    View publication on PubMed
Search for more literature for 2.7.1.154

Cloned(Commentary)

Cloned (Comment) Organism
the region of human PI3K-C2alpha cDNA corresponding to residues 2-144 is cloned into the SmaI-ECoRI sites of pGEX-2T, the fusion protein is expressed in Escherichia coli BL21, transfection to COS cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane colocalization of the enzyme with plasma membrane-coated pits in COS-cells Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking ?
-
 ?
additional information Homo sapiens PI3K-C2alpha the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 PI3K-C2alpha
-
Homo sapiens PI3K-C2alpha
-
 PI3K-C2alpha
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking Homo sapiens ?
-
 ?
additional information the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking Homo sapiens PI3K-C2alpha ?
-
 ?