Literature summary for 2.7.1.153 extracted from

Kim, J.J.; Choi, Y.M.; Hong, M.A.; Hwang, S.S.; Yoon, S.H.; Chae, S.J.; Jee, B.C.; Ku, S.Y.; Kim, J.G.; Moon, S.Y.
Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene Met326Ile polymorphism in women with polycystic ovary syndrome (2009), Hum. Reprod., 24, 1184-1190.

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Cloned(Commentary)

Cloned (Comment)	Organism
PI 3-kinase genotyping	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
M326I	a common naturally occuring polymorphism of the regulatory subunit p85alpha in women involved in the polycystic ovary syndrome, PCOS, genotyping in polycystic ovary syndrome patients from Korean female population	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	Korean population, women with polycystic ovary syndrome	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	-	Homo sapiens	-

Subunits

Subunits	Comment	Organism
heterodimer	catalytic subunit p110 and regulatory subunit p85	Homo sapiens

Synonyms

Synonyms	Comment	Organism
PI 3-kinase	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	PI 3-kinase is an important enzyme in the early insulin signaling cascade and plays a key role in insulin-mediated glucose transport	Homo sapiens

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Release 2023.1 (January 2023)