Literature summary for 2.7.1.145 extracted from

Fatima, M.; Ahmed, M.; Batool, F.; Riaz, A.; Ali, M.; Munch-Petersen, B.; Mutahir, Z.
Recombinant deoxyribonucleoside kinase from Drosophila melanogaster can improve gemcitabine based combined gene/chemotherapy for targeting cancer cells (2019), Bosn. J. Basic Med. Sci., 19, 342-349 .

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Application

Application	Comment	Organism
medicine	the recombinant enzyme is used to sensitize human cancer cell lines to gemcitabine	Drosophila melanogaster

Cloned(Commentary)

Cloned (Comment)	Organism
the enzyme with a deletion of the last 20 amino acid residues is expressed in MCF-7-R cells	Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + a 2'-deoxyribonucleoside	Drosophila melanogaster	-	ADP + a 2'-deoxyribonucleoside 5'-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	Q9XZT6	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + a 2'-deoxyribonucleoside	-	Drosophila melanogaster	ADP + a 2'-deoxyribonucleoside 5'-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
deoxyribonucleoside kinase	-	Drosophila melanogaster
dNK	-	Drosophila melanogaster

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Release 2023.1 (January 2023)