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Literature summary for 2.7.1.145 extracted from

  • Clausen, A.R.; Girandon, L.; Knecht, W.; Survery, S.; Andreasson, E.; Munch-Petersen, B.; Piskur, J.
    A multisubstrate deoxyribonucleoside kinase from plants (2008), Nucleic Acids Symp. Ser., 52, 489-490.
    View publication on PubMed
Search for more literature for 2.7.1.145

Cloned(Commentary)

Cloned (Comment) Organism
upon expression in Escherichia coli, enzyme sensitizes cells against various nucleic acid analogs such as gemcitabine Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine + ATP specificity constant 33000 per s and M Arabidopsis thaliana 2'-deoxyadenosine 5'-phosphate + ADP
-
 ?
2'-deoxycytidine + ATP specificity constant 18000 per s and M Arabidopsis thaliana 2'-deoxycytidine 5'-phosphate + ADP
-
 ?
2'-deoxyguanosine + ATP specificity constant 10000 per s and M Arabidopsis thaliana 2'-deoxyguanosine 5'-phosphate + ADP
-
 ?
2'-deoxyuridine + ATP specificity constant 410 per s and M Arabidopsis thaliana 2'-deoxyuridine 5'-phosphate + ADP
-
 ?
bromovinyldeoxyuridine + ATP specificity constant 930 per s and M Arabidopsis thaliana bromovinyldeoxyuridine 5'-phosphate + ADP
-
 ?
difluorodeoxycytidine + ATP i.e. gemcitabine. Efficient in vivo phosphorylation, specificity constant 4800 per s and M Arabidopsis thaliana difluorodeoxycytidine 5'-phosphate + ADP
-
 ?
additional information no substrate: deoxythymidine Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
AGCK
-
 Arabidopsis thaliana