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Literature summary for 2.7.1.138 extracted from

  • Hinkovska-Galcheva, V.; Clark, A.; VanWay, S.; Huang, J.B.; Hiraoka, M.; Abe, A.; Borofsky, M.; Kunkel, R.G.; Shanley, T.; Shayman, J.A.; Lanni, F.; Petty, H.R.; Boxer, L.A.
    Ceramide kinase promotes Ca2+ signaling near IgG-opsonized targets and enhances phagolysosomal fusion in COS-1 cells (2008), J. Lipid Res., 49, 531-542.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression of hCERK in COS-1 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
caveola CERK and localizes to the caveolar microdomains during phagocytosis Homo sapiens 5901
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ceramide + ATP Homo sapiens increased ceramide 1-phosphate during phagocytosis enhances phagocytosis and phagolysosome formation in COS-1 cells expressing hCERK ceramide 1-phosphate + ADP
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ceramide + ATP
-
 Homo sapiens ceramide 1-phosphate + ADP
-
 ?
ceramide + ATP increased ceramide 1-phosphate during phagocytosis enhances phagocytosis and phagolysosome formation in COS-1 cells expressing hCERK Homo sapiens ceramide 1-phosphate + ADP
-
 ?

Synonyms

Synonyms Comment Organism
CERK
-
 Homo sapiens
hCERK
-
 Homo sapiens