Application | Comment | Organism |
---|---|---|
medicine | ceramide kinase is important for neutrophil homeostasis, ceramide kinase is important for the defense against Streptococcus pneumoniae infections | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Mus musculus | 5794 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ceramide + ATP | Mus musculus | ceramide kinase is not the only source of ceramide 1-phosphate, ceramide kinase is important for neutrophil homeostasis, ceramide kinase is important for the defense against Streptococcus pneumoniae infections | ceramide 1-phosphate + ADP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Mus musculus | - |
leukocyte | - |
Mus musculus | - |
macrophage | bone marrow-derived macrophage, BMDM | Mus musculus | - |
mast cell | bone marrow-derived mast cell | Mus musculus | - |
neutrophil | - |
Mus musculus | - |
peritoneal macrophage | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000000004 | - |
liver of wild-type mice | Mus musculus |
0.000000028 | - |
kidney of wild-type mice | Mus musculus |
0.000000038 | - |
pancreas of wild-type mice | Mus musculus |
0.000001191 | - |
testis of wild-type mice | Mus musculus |
0.00000141 | - |
cerebellum of wild-type mice | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ceramide + ATP | - |
Mus musculus | ceramide 1-phosphate + ADP | - |
? | |
ceramide + ATP | ceramide kinase is not the only source of ceramide 1-phosphate, ceramide kinase is important for neutrophil homeostasis, ceramide kinase is important for the defense against Streptococcus pneumoniae infections | Mus musculus | ceramide 1-phosphate + ADP | - |
? | |
N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl-D-erythrosphingosine + ATP | - |
Mus musculus | N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl-D-erythrosphingosine 1-phosphate + ADP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CERK | - |
Mus musculus |