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Literature summary for 2.7.1.138 extracted from

  • Tsuji, K.; Mitsutake, S.; Yokose, U.; Sugiura, M.; Kohama, T.; Igarashi, Y.
    Role of ceramide kinase in peroxisome proliferator-activated receptor beta-induced cell survival of mouse keratinocytes (2008), FEBS J., 275, 3815-3826.
    View publication on PubMed
Search for more literature for 2.7.1.138

Activating Compound

Activating Compound Comment Organism Structure
peroxisome proliferator-activated receptor beta upregulation of CERK through activation of peroxisome proliferator-activated receptor beta (PPARbeta) results in decreased intracellular ceramide levels and increased cell survival with less cell death Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ceramide + ATP Mus musculus CerK and C1P are involved in many cell functions, including membrane fusion, phagocytosis and degranulation in mast cells ceramide 1-phosphate + ADP
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte mouse keratinocyte cell line SP1 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ceramide + ATP
-
 Mus musculus ceramide 1-phosphate + ADP
-
 ?
ceramide + ATP CerK and C1P are involved in many cell functions, including membrane fusion, phagocytosis and degranulation in mast cells Mus musculus ceramide 1-phosphate + ADP
-
 ?

Synonyms

Synonyms Comment Organism
CERK
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 Mus musculus