Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.138 extracted from

  • Mitra, P.; Maceyka, M.; Payne, S.G.; Lamour, N.; Milstien, S.; Chalfant, C.E.; Spiegel, S.
    Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells (2007), FEBS Lett., 581, 735-740.
    View publication on PubMed
Search for more literature for 2.7.1.138

Inhibitors

Inhibitors Comment Organism Structure
siRNA downregulation of CerK with siRNA targeted against Cerk reduced cellular proliferation within 48 hours Homo sapiens
siRNA downregulation of CerK with siRNA targeted against Cerk reduced cellular proliferation within 48 hours Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 SDS-PAGE Mus musculus
62000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ceramide + ATP Mus musculus
-
 ceramide 1-phosphate + ADP
-
 ?
ceramide + ATP Homo sapiens
-
 ceramide 1-phosphate + ADP
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
A-549 cell human lung adenocarcinoma cell Homo sapiens
-
fibroblast
-
 Homo sapiens
-
lung adenocarcinoma cell
-
 Homo sapiens
-
NIH-3T3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ceramide
-
 Homo sapiens ADP + ceramide 1-phosphate
-
 ?
ceramide + ATP
-
 Mus musculus ceramide 1-phosphate + ADP
-
 ?
ceramide + ATP
-
 Homo sapiens ceramide 1-phosphate + ADP
-
 ?

Synonyms

Synonyms Comment Organism
CERK
-
 Mus musculus
CERK
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens