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Literature summary for 2.7.1.138 extracted from
- Identification of a nuclear localization signal in the retinitis pigmentosa-mutated RP26 protein, ceramide kinase-like protein (2006), Biochem. Biophys. Res. Commun., 343, 982-987.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| CERKL | the point mutant enzyme CERKL does not phosphorylate ceramide or diacylglycerol and is localized in the nucleus | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Homo sapiens | 5886 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| anti-FLAG M2 affinity gel chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
| HeLa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + ceramide | - |
Homo sapiens | ADP + ceramide 1-phosphate | - |
? |  |
| ATP + diacylglycerol | - |
Homo sapiens | ADP + diacylglycerol 1-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CERK | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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