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BRENDA support

Literature summary for 2.7.1.137 extracted from

  • Schnell, C.R.; Stauffer, F.; Allegrini, P.R.; OReilly, T.; McSheehy, P.M.; Dartois, C.; Stumm, M.; Cozens, R.; Littlewood-Evans, A.; Garcia-Echeverria, C.; Maira, S.M.
    Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging (2008), Cancer Res., 68, 6598-6607.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NVP-BEZ235 the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin catalytic inhibitor, interferes with tumor growth likely by affecting tumor cells and their vasculature system Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
Homo sapiens
-