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Literature summary for 2.7.1.137 extracted from

  • Phillips, W.A.; St.Clair, F.; Munday, A.D.; Thomas, R.J.S.; Mitchell, C.A.
    Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors (1998), Cancer, 83, 41-47.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme is involved in the signaling pathways regulating cell growth by virtue of its activation in response to various mitogenic stimuli ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon colorectal tumors exhibit enhanced PI 3-kinase activity compared with normal colonic mucosa Homo sapiens
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colonic mucosa colorectal tumors exhibit enhanced PI 3-kinase activity compared with normal colonic mucosa Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidylinositol
-
 Homo sapiens ADP + phosphatidylinositol 3-phosphate
-
 ?
additional information enzyme is involved in the signaling pathways regulating cell growth by virtue of its activation in response to various mitogenic stimuli Homo sapiens ?
-
 ?