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BRENDA support

Literature summary for 2.7.1.137 extracted from

  • Ahmad, F.; Li, P.M.; Meyerovitch, J.; Goldstein, B.J.
    Osmotic loading of neutralizing antibodies demonstrates a role of protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway (1995), J. Biol. Chem., 270, 20503-20508.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information in cells loaded with protein-tyrosine phosphatase antibody, phosphatidylinositol 3'-kinase activity is increased by 38%, respectively, compared with control cells loaded with preimmune IgG Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
cell culture KRC-7 hepatoma cells Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidylinositol
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Rattus norvegicus ADP + phosphatidylinositol 3-phosphate
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