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Literature summary for 2.7.1.136 extracted from

  • Chesneau, O.; Tsvetkova, K.; Courvalin, P.
    Resistance phenotypes conferred by macrolide phosphotransferases (2007), FEMS Microbiol. Lett., 269, 317-322.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
mph genes cloned into Escherichia coli AG100A Escherichia coli
mph genes cloned into Escherichia coli AG100A Salmonella enterica subsp. enterica serovar Typhimurium
mph genes cloned into Escherichia coli AG100A uncultured bacterium

Organism

Organism UniProt Comment Textmining
Escherichia coli Q47396 plasmid pLEW517
-
Salmonella enterica subsp. enterica serovar Typhimurium Q5QJG2
-
-
uncultured bacterium A0AEF2
-
-
uncultured bacterium Q5W3B4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin Escherichia coli ADP + azithromycin 2'-O-phosphate
-
?
ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin Salmonella enterica subsp. enterica serovar Typhimurium ADP + azithromycin 2'-O-phosphate
-
?
ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin uncultured bacterium ADP + azithromycin 2'-O-phosphate
-
?
ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin Escherichia coli ADP + telithromycin 2'-O-phosphate
-
?
ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin Salmonella enterica subsp. enterica serovar Typhimurium ADP + telithromycin 2'-O-phosphate
-
?
ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin uncultured bacterium ADP + telithromycin 2'-O-phosphate
-
?